BACKGROUND:Pneumonia and pneumococcal disease cause a large disease burden in resource-constrained settings.We pursue an extended cost-effectiveness analysis (ECEA) of two fully publicly financed interventions in Ethiopia: pneumococcal vaccination for newborns and pneumonia treatment for under-five children in Ethiopia.METHODS:We apply ECEA methods
Delayed inflammation associated with retained perfluorocarbon liquid
A 55-year-old woman, with history of cataract surgery 1 year back, presented with features of ocular inflammation for last 3 months.She had no history of any other intraocular surgery.On examination, anterior segment showed frothy material in the inferior angle with moderate anterior chamber reaction (cells+/flare+) and sulcus intraocular lens with
Hmgcr in the corpus allatum controls sexual dimorphism of locomotor activity and body size via the insulin pathway in Drosophila.
The insulin signaling pathway has been implicated in several physiological and developmental processes.In mammals, it controls funko wall-e grande expression of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGCR), a key enzyme in cholesterol biosynthesis.In insects, which can not synthesize cholesterol de novo, the HMGCR is implicated in the biosynthe
Making the most of existing data in conservation research
Much attention in recent years has been focused on making biodiversity data open and accessible to researchers.Yet ensuring the availability of these data is only the first step in preventing data waste.Here, we argue that researchers need to do a better job of using available datasets.We recommend that researchers search for existing data sources